Immunoadsorption Apheresis

Immunoadsorption Apheresis is particularly suitable for supporting the immune system of patients with autoimmune diseases, in which the immune system attacks its own body cells. Immunoadsorption Apheresis is a method of therapeutic apheresis, i.e. it serves to remove pathogenic blood components. This procedure often leads to an improvement when therapy with pharmacologically active substances is no longer effective. In addition, Immunoadsorption Apheresis is a suitable therapy option for diseases triggered by auto-antibodies from the IgG class.

Immunoadsorption is a direct procedure in which autoantibodies are quickly and effectively removed from the patient's bloodstream. To achieve this, 2 Globaffin adsorbers, synthetic broadband immune adsorbers with peptide GAM ligand, are used. These efficiently remove immune complexes and above all immunoglobulins (IgG). The plasma, continuously obtained using a cell separator, is passed through one of the two double adsorbers (GLOBAFFIN®) for immune adsorption and is thus freed of antibodies and immune complexes. The treated plasma is recombined with the blood and reinfused to the patient.

Patients who are treated with two and a half times the plasma volume for five consecutive days, usually experience a 95% reduction in IgG antibody levels.

The IgG adsorbers are used to treat ailments and diseases from various indication areas.